Die Wirkung von Substanzen…
Pharmakologisches Institut der Universität Bern/Schweiz

NOTE: This plain text article interpretation has been digitally created by OCR software to estimate the article text, to help both users and search engines find relevant article content.  To read the actual article text, view or download the PDF above.

Has just been published:

Oktober 1956

The effect of substances on the network construction of the spider as a biological test

Outside lecturer

Dr. Peter N. Witt

Institute of Pharmacology of the University of Bern / Switzerland

With 49 illustrations. III, 79 pages Gr.-8 °. 1956. Stiff stapled DM 15-60

Fig. 15 net for a high caffeine dose

SPRINGER -ver LA G / BERLIN – Göttingen – HEIDELBERG

To be obtained through any bookshop

WITT PN

The effect of! Spider substances on the network construction of r

al Ip ^ gic # Test

v Springer Verlag, Berlin, 1956 • •

L’A. studiÖÄ questa original monografia ¡’azione; delle Sostanze ottenute dalla rete di un ragno; la Zilia notata come test biologico.

Dopo avere minutamente descritta ¿l;%> lavorazione della rete da parte del Ragno di questa specie, ne analizza i Componenti chimici- li esamina dal plinto di £ vista farmt cologico, e ci rivela i risultati delle Ricerche paragonando sue le Sostanze in ESSA contenute con le identiche Sostanze esistenti nell’uómó;

CHIUDE la. sua dimostrazione illustrando la valutazione dei risultati ottenuti.

Un’ampia bibliografia e Posta alla fine dell’opuscolo che anche Contiene numerose e bellissime illustrazioni.

Witt, the effect of substances

in the network construction of the spider as a biological Tesi

To the benefit of a pharmacological method for1, to assess a particular issue, you should review its technical. Implementation; – “the results gained so far with her and their requirements known. This book covers all aspects of a method 3, the (mainly those with centralnervösem attack point) uses the Netzbauhandlung the spider for registering drug effects. Even the zoological less Preformed should because of text and numerous illustrations accompanying the spider Zilla-x-notata CI. can be found in nature, they begin and the regular network construction in the laboratory

Witt, the effect of substances

in the network construction of the spider as a biological test

Fig. 48. Power to Xylopropamin

bring. The Normalmaßzahlen gained on hundreds of networks can be drug-related deviations quickly realize and a list of previously detected changes under influence of the substance allowed the classification of new substances according to their biological activity. Although the hereditary mechanism is the network construction is based is unknown, give anatomy and animal psychology considerations hints on how the changes in Netzbauhandlung could be interpreted by medication. A comparison between Spider and man in relation to drug effects and sensory physiology serves as a warning that the test results can not be transferred immediately.

Springer-Verlag / BERLIN GOTTINGEN – HEIDELBERG

Witt, the effect of substances on the network construction of the spider as a biological test

Contents

Introduction.

Spider’s Web Zilla-x-notata.

The preparation of the network.

Analysis of Netzbauverhaltens: The network construction seen animals psychologically. – Triggering the Netzbaues. – Influence of temperature and light on the Netzbauhäufigkeit spider (own tests). – Interruption of Netzbaues by molting. – Phases of Netzbaues. – Handlebars of Netzbaues. – Some of the test Important from the anatomy of Zilla.

The Netzbauverhalten of Zilla-x-notata CI. as pharmacological test method: Fang. – Breeding. Life. – Attitude, Fiss diet. – Pharmacological methodology. – Normal degree of Zilla network. – Application and dose. – Test duration and ÿmeïige. r

Results in the pharmacological experiment, compared with the known effects of the same substances in humans: Mescalinsulfat © / 4

3,5 diiodo-4-methoxy-yS-phenethylamine. – Pervitin. – Scopolamine. – Caffeine. –

Strychnin.-d-lysergic acid diethylamide LSD 25 – Largactil. – Benzopyran 122. – adenochrome. – Adrenoxyl. – HI substance. – Nembutal. – Xylopropamin. –

Origin of the substances.

Evaluation of test results: identification of the substances in comparison with other tests. – Variation of specific criteria. – Comparison of the effects of substances on humans and spider.

Bibliography.

General Physiology

From Albrecht Bethe, professor emeritus at the University of Frankfurt am Main. With 159 illustrations. VI, 294 pages Gr.-8 °. 1952. Ganzleinen DM 29.70

Lectures on developmental physiology

VonProfessorDr. Alfred Kühn, Tübingen. Mit477Textabbildungen. IX, 506Seiten Gr.-8 °. 1955 – Ganzleinen DM 43.60

9- 56. 360th

i